MicroRNA-34b inhibits prostate cancer through demethylation, active chromatin modifications and AKT pathways
نویسندگان
چکیده
Shahana Majid, Altaf A Dar, Sharanjot Saini, Varahram Shahryari, Sumit Arora, Mohd Saif Zaman, Inik Chang, Soichiro Yamamura, Yuichiro Tanaka, Takeshi Chiyomaru, Guoren Deng and Rajvir Dahiya. 1 Department of Urology, VA Medical Center and UCSF, San Francisco, California 94121 2 California Pacific Medical Center Research Institute, 475 Brennan St., San Francisco, California. 94107
منابع مشابه
miRNA-34b inhibits prostate cancer through demethylation, active chromatin modifications, and AKT pathways.
PURPOSE miRNAs can act as oncomirs or tumor-suppressor miRs in cancer. This study was undertaken to investigate the status and role of miR-34b in prostate cancer. EXPERIMENTAL DESIGN Profiling of miR-34b was carried out in human prostate cancer cell lines and clinical samples by quantitative real-time PCR and in situ hybridization. Statistical analyses were done to assess diagnostic/prognosti...
متن کاملHuman Cancer Biology miRNA-34b Inhibits Prostate Cancer through Demethylation, Active Chromatin Modifications, and AKT Pathways
Purpose:miRNAs can act as oncomirs or tumor-suppressormiRs in cancer. This studywas undertaken to investigate the status and role of miR-34b in prostate cancer. Experimental Design: Profiling of miR-34b was carried out in human prostate cancer cell lines and clinical samples by quantitative real-time PCR and in situ hybridization. Statistical analyses were done to assess diagnostic/prognostic p...
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